Cystic Fibrosis Research Today is a free monthly online journal that collates and summarizes the latest research about Cystic Fibrosis, including details on symptoms, genetics, treatment, information.

High-resolution computed tomography of the lung in children with cystic fibrosis: technical factors.

Long FR

Department of Radiology, Columbus Children's Hospital, Ohio State University, Columbus, Ohio 43205-2696, USA. flong@chi.osu.edu

A standard technique that controls for respiratory motion and lung volumes during imaging is necessary if high-resolution computed tomography is to be used as an outcome measure in children with cystic fibrosis. End-inspiratory and expiratory imaging allows for the detection and differentiation of early lung disease. In children ages 0-5 years, a noninvasive controlled ventilation technique is ideal, and can be used in combination with raised-volume infant pulmonary function tests. In older children, a spirometric-assisted or spirometric-triggered technique should be used. With optimal technique, radiation dose settings (kVp and mA) can be lowered to achieve a diagnostic screening high-resolution computed tomography of the lungs at a dose equivalent to that of the chest radiograph.

Published 26 July 2007 in Proc Am Thorac Soc, 4(4): 306-9.
Full-text of this article is available online (may require subscription).

© 2004-2008 Cystic Fibrosis Research Today. All Rights Reserved.